Aripiprazole Lauroxil
Aripiprazole Lauroxil
CAS: 1259305-29-7
Molecular Formula: C36H51Cl2N3O4
Aripiprazole Lauroxil - Names and Identifiers
Aripiprazole Lauroxil - Physico-chemical Properties
| Molecular Formula | C36H51Cl2N3O4 |
| Molar Mass | 660.71384 |
| Density | 1.153±0.06 g/cm3(Predicted) |
| Melting Point | 83 - 84°C |
| Boling Point | 781.7±60.0 °C(Predicted) |
| Water Solubility | Chloroform (Slightly), Methanol (Slightly, Sonicated) |
| Appearance | Form Solid color White to Off-White |
| pKa | 7.67±0.10(Predicted) |
| Storage Condition | Refrigerator, under inert atmosphere |
| Physical and Chemical Properties | Lauroyl aripiprazole was approved by the U.S. Food and Drug Administration (FDA) in October 2015. It is an aripiprazole sustained-release long-acting injection produced by Waltham Alkermes Company in Massachusetts, namely lauroyl aripiprazole (Aripiprazole lauroxil, trade name Aristada), which is used to treat adult schizophrenia. |
Aripiprazole Lauroxil - Introduction
Dosage The drug is injected every 4-6 weeks at the upper arm or buttocks.
The characteristic of lauroyl aripiprazole is generally well tolerated, and the safety data are comparable to the oral dosage form of aripiprazole.
Adverse reactions Insomnia, akathisia and headache.
Note that the instructions of this product have a black box warning, indicating that the drug exceeds the indications for the treatment of senile dementia-related psychosis or increases the risk of death.
References [1] Anonymous. FDA Approved Lauroyl Aripiprazole Sustained Release Injection for Schizophrenia Treatment [J]. World Clinical Drugs, 2015(10):719-719.
Xia Xunming. FDA Approved Aristada (aripiprazole lauroxil) Injection for Treatment of Schizophrenia [J]. Journal of Guangdong Pharmaceutical University, 2015(5):584-584.
Last Update：2024-04-09 20:52:54
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